Effective oral surgery hemostasis is crucial for preventing complications and optimizing healing. While traditional methods (pressure, sutures, sponges) still dominate, autologous platelet concentrates, PRP and PRF, as well as newer topical agents, are gaining popularity. This systematic review assesses emerging trends and examines the clinical outcomes of various hemostatic techniques, focusing on high-risk groups such as anticoagulated patients. Findings demonstrate that biological agents such as PRF are capable of shortening bleeding time and stabilizing wounds and frequently allow procedures to be performed without the need for anticoagulation therapy. There is reasonable support for these new methods; however, further high-quality research is needed to define standard protocols.
