Photodynamic therapy is a modern, rapidly evolving discipline for treating various diseases & conditions. It is a light-mediated photochemical reaction involving the activation of photosensitizing compounds leading to the generation of cytotoxic reactive oxygen species. Photodynamic therapy represents a non-invasive, non-toxic, repeatable procedure without causing any collateral damage and is used for treating periodontal and peri-implant diseases by causing light-activated microbial killing and also in the treatment of various oral potentially malignant disorders (OPMDs). Photodynamic therapy was performed using an application of photosensitizing dye (1% methylene blue) and a low-level diode laser (660nm at 50mW) for one minute. Three different modalities i.e., management of periodontitis, peri-implantitis & oral lichen planus are showcased in this case series where PDT was effective in improving the clinical parameters of periodontitis & peri-implantitis cases and overall clinical improvement of symptoms in case of oral lichen planus. Thus, proving the PDT as a promising treatment adjunctive.
