This article presents a method of mechanical processing of structural material for the manufacture of individual transcendental implants used to restore the biomechanical characteristics of teeth with a resected root. The technique is reproduced utilizing in-line exposure to zirconium dioxide stabilized with yttrium, aluminum oxide powder of a certain dispersion and particle diameter, under a pressure of 2 atmospheres. Additionally, the influence of structural material and artificially created surface roughness of individual transcendental zirconium dioxide implants on the formation of bone tissue in the jawbones of experimental animals was studied. Samples of individual transcendental implants were fixed in artificially created critical defects of the mandible of laboratory rabbits. Histological preparations were prepared in dynamics, at the time of withdrawal of animals from the experiment 1, 3, 6, and 9 months after surgery. The obtained results indicated the formation of mature bone tissue in the intraoperative defect around analogs of transcendental implants and the absence of inflammatory and macrophage reactions in dynamics. This indicates the biocompatibility, bioinertness, and effectiveness of zirconium dioxide as material for dental implants.