In orthodontics, extraction remains a controversial and multidisciplinary choice. In some instances, the understanding of the treatment outcomes and relapse rate has its importance. However, different literature needs to be assessed on the effectiveness of mandibular incisal extraction (MIE) among non-growing patients as an alternative treatment modality. This review was done following a particular focus question: "Is mandibular incisor extraction being a common choice in orthodontic treatment planning to resolve the crowing among non-growing patients?" under the PICO standards. Data selection strategy followed the methodology of PRIZMA guidelines using keywords. Studies in humans that included MIE, published in high impact journals, in the English language, from 2015 to 2020, among non-growers from both genders were included. However, irrelevant studies to the current review, case reports, systematic reviews, opinions, and survey-based cross-sectional studies were excluded following strict eligibility criteria.
From different electronic databases "Saudi Digital Library, Clarivate, Cochrane Library, Google Scholar, and Pubmed". 6273 studies were identified, 1668 were recorded after duplicates were removed. Subsequently, going through the title and abstract, 1653 were eliminated due to multiple reasons. 15 articles were read in the full test; only 8 articles were chosen after qualitative assessment. The risk of bias was apprised by one reviewer as all provided level I & II evidence. Significant agreement about the most frequent indications of MIE was mandibular crowding and skeletal class III camouflage. An unclear correlation was found between MIE, premolar extraction in terms of post-treatment relapse.