Over the past decades in Russia, the most common form of proinflammatory diseases of the maxillofacial region (MFO) has remained odontogenic inflammatory diseases, accounting for 26% of the total number of inflammatory diseases. The question of the diagnosis and treatment of abscesses and phlegmons, leading to a large number of formidable complications, remains quite relevant. The development of new approaches in the treatment of inflammatory diseases with the use of phytoadoptogenic was the aim of the study. According to the results obtained, in animals that were on classical antibacterial treatment in combination with an adaptogen, there was an improvement in clinical symptoms in the early stages, a significant decrease in the qualitative and quantitative composition of microflora. Thus, the use of adaptogens in the treatment of inflammatory diseases is advisable. As result, it is concluded that adaptogens must be pronounced modifiers of the body's reactivity, which makes it expedient to use them in the treatment of inflammatory diseases of the maxillofacial region.