With the evolution of CAD/CAM technology, obtaining accurate digital data has become important for the long-term success of prostheses. The present work focuses on systematically identifying and evaluating the literature on the digitization process using CBCT for fabricating CAD/CAM crowns and comparing it to those obtained using routine scanners to assess fit. Using the PRISMA guidelines. The keywords were “In teeth requiring full veneer crowns (P), does the scanning technique (I) provide better accuracy and marginal fit (O) compared with the routine digital methods of fabrication (C). A comprehensive electronic search from 2015 to January 2023 was done. All the studies comparing the fit of prostheses fabricated using CBCT and intra-oral scanners were included. An electronic database search identified 260 articles. 4 studies were included to meet the research question. All 4 studies analyzed the marginal discrepancies of crowns fabricated digitally using CBCT. There was no statistically significant difference observed in the marginal fit of crowns. Limited studies are available comparing the fit of crowns fabricated using CBCT, intraoral scanners, and extraoral scanners. The current systematic review identifies the need for high-quality trials evaluating the accuracy and fit of the crowns/ prostheses fabricated by using CBCT scans as the intra-oral scanners.