Understanding bone biology before the placement of an implant is a key factor in successful implant survival. The purpose of the study is to assess bone turnover markers as a diagnostic tool for the evaluation of bone quality in patients undergoing dental implant surgery prior to the treatment. The present study is a single-center, case–control, cross-sectional study done in a private institution, chennai. Patients with single edentulous space for the past 6 months were selected for the study. BTM (Bone Turnover Markers) levels from saliva samples collected concurrently with regularly scheduled blood tests before implant surgery were evaluated with Enzyme-linked immunosorbent assay ELISA. The values were compared in SPSS software using an independent t-test. Bone turnover markers such as BALP, Osteocalcin, CTX-1, and NTX-1 were increased in osteoporotic patients (p<0.05) which showed an increased chance of failure of the dental implant. Assessing bone turnover markers from saliva can serve as a successful tool in assessing the bone level for placement of dental implants and aids treatment planning. The difference in bone turnover markers serves as a promising biological tool in evaluating the jawbone condition in addition to the radiological examination for implant placement.
