Ameloblastoma is a unique epithelium odontogenic tumor occurring in the posterior region of the mandible. It is initially asymptomatic but slowly leads to the expansion of the cortical bone. Ameloblastoma can be categorized into different variants based on clinical and histological features. Amongst all the variants of ameloblastoma solid multicystic ameloblastoma (SMA) considered to be a locally aggressive lesion. It can present different clinical, radiographic and histopathological presentations. Due to inappropriate management, it is associated with a high rate of recurrence. Proper diagnosis is very crucial for the appropriate management of ameloblastoma. Ameloblastoma can be treated by wide local excision and reconstruction of the defect. In this report, we have a case of SMA of the mandible, which was initially misdiagnosed and has an unusual presentation.
