%0 Journal Article
%T Effect of Non-Surgical Periodontal Therapy (NSPT) on Salivary Glutathione Reductase (GR) in Smokers and Periodontitis Subjects
%A Priyanka Kakade
%A Sameer A. Zope
%A Girish Suragimath
%A Siddhartha Varma
%A Apurva Kale
%A Vaishali Mashalkar
%J Annals of Dental Specialty
%@ 2347-2022
%D 2022
%V 10
%N 4
%R 10.51847/WZghL73bwK
%P 109-116
%X Deranged antioxidant status may play a role in the extreme tissue breakdown in periodontitis. Apart from periodontitis, smoking also plays a major contributing role in increasing oxidative stress of periodontal tissues. Hence this study aimed to evaluate & compare the salivary Glutathione Reductase (GR) levels following non-surgical periodontal therapy (NSPT) in smokers and non-smokers with and without periodontitis. A total of 76 subjects were divided into four groups smokers with Periodontitis (n = 19), smokers without Periodontitis (n = 19), non-smokers with periodontitis (n = 19), and non-smokers without periodontitis (n = 19). Clinical parameters such as plaque index (PI), gingival index (GI) probing pocket depth (PPD), and clinical attachment level (CAL) were assessed at baseline, on the 14th day, and at 1 month. Salivary GR levels were analyzed by ELISA pre and post-NSPT. NSPT was associated with improvement in PI and GI scores. Significant reduction in PPD and gain in CAL were observed post-NSPT (p
%U https://annalsofdentalspecialty.net.in/article/effect-of-non-surgical-periodontal-therapy-nspt-on-salivary-glutathione-reductase-gr-in-smokers-ji7g6omplsm3rka